Charles River Laboratories Sr. Scientist in South San Francisco, California

Sr. Scientist

Req ID #: 34464

Location: South San Francisco, CA, US, 94080

For nearly 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Enhancing our global leadership in providing drug discovery and development products and services to the pharmaceutical and biotech industries, Charles River is launching a discovery DMPK services (non-GLP) in our South San Francisco site. We seek to enhance our services’ value to our clients by increasing our ease of doing business with, shortening timelines and developing deeper collaborative partnerships with our clients, all enabled by our proximity to and embeddedness in this critically important biotech research hub and ecosystem.

We are seeking a highly motivated, enthusiastic and self-directed Bioanalytical Scientist who enjoys creating and building an exceptional team providing non-GLP, discovery bioanalytical services. This is an exciting position that will be most suited for someone who is looking to be involved in the early stage of the lab set up. The individual in this position will be responsible for the scientific and operational management as well as client relationship development and maintenance within the South San Francisco site for this service.

The following are minimum requirements related to theDiscovery Bioanalytical Sr. Scientist position.

  • Exceptional interpersonal skills and demonstrated ability to mentor, develop and lead high performing teams

  • Ability to establish strong and high functioning relationships with colleagues and clients is critical

  • Excellent organizational and planning skills enabling management of multiple, concurrent tasks & priorities

  • Demonstrated competencies in both the theoretical and practical principles of bioanalysis supporting drug discovery in-vivo drug metabolism pharmacokinetics

  • Accomplished skills in all practical aspects of non-GLP bioanalysis supporting PK screening, functioning independently as the Principal Investigator and technical resource, developing, applying and troubleshooting LC/MS-based methods for the analysis of small molecule drug compounds in a wide variety of nonclinical species sample matrices.

  • Excellence in abilities to serve as client point of contact for all aspects of bioanalytical studies placed with the site, including assay design, scheduling, logistics management and regular communication with clients

  • Proficiency in performing effective assay troubleshooting in all aspects, from assay design, extraction, instrumentation and data interpretation

  • Demonstrated understanding of and commitment to excellence in all aspects of client service and development and maintenance or deep relationships

  • Ensure compliance to all company policies, procedures and applicable regulations.

  • Proficiency in the use of standard software including Microsoft® Excel, Word, Powerpoint, etc. Proficiency with using Watson highly desirable.

  • Education: Bachelor's degree (B.S./B.A.) or equivalent in Analytical Chemistry or closely related scientific discipline. Related Master's degree (M.S./M.A.) or PhD preferred.

  • Experience: Minimum of 9 years related experience in the contract research, academic, or pharmaceutical industry.

  • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above.


Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 320 patents and 74 preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

About Charles River

Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 11,000 employees within 70 facilities in 18 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2016, revenue increased by 23.3% to $1.68 billion from $1.36 billion in 2015.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of 70% of the drugs approved by the FDA in 2016.

For more information, please

Equal Employment Opportunity

Charles River Laboratories, Inc. is an Equal Opportunity Employer M/F/Disabled/Vet